The first thing Peter gave up was Judaism. The heavenly vision was contradictory to the religion of his forefathers. Peter's attitude was not to stand with his forefathers' religion but to stand with the heavenly vision. In the first several chapters of Acts, we see that Peter and the other apostles were troubled and persecuted by Judaism, but they continued to take sides with the heavenly vision. The first item of their consecration in the upper room was to give up the traditional religion of their forefathers.
In order to be in the upper room, Peter also gave up his country. Peter was from Galilee, but he left Galilee and came to the upper room in Jerusalem.
As a native of Galilee, Peter surely had relationships with his neighbors and friends in Galilee. For Peter to be in the upper room required that he give up these relationships. This is not an insignificant matter. Peter gave up these relationships at a real cost.
Peter also gave up his relatives. I doubt whether Peter brought his parents with him into the upper room. There is no hint to this effect. Actually, Peter's parents might have remained in Judaism.
Finally, Peter was in the upper room at the risk of his life. He was ready to give up his life. At that time Jerusalem was a threatening place to Peter and all the others in the upper room, yet they were willing to risk their lives to be there. In order to be in the upper room, they all gave up Judaism, their country, their neighbors and friends, and their relatives, and they were willing to risk their lives.